oCelloScope is a unique live-cell imaging system for sensitive and detailed monitoring of biological growth and development. It’s an easy-to-use automated microscope facilitating high-throughput testing and robust time-lapse studies..
The optical axis is tilted 6.25° relative to the horizontal plane. Such tilting facilitates the scanning of volumes by recording a series of images to form an image stack. The tilting enables more freedom of operation at both high and low concentrations of analyte (microorganisms, mammalian cells, spores, pollen, etc.). The image acquisition process is repeated over time and the time-lapse sequence of best-focus images is used to generate a video.
oCelloScope’s UniExplorer software provides instrument control and data analysis. The optimised algorithms implemented in UniExplorer allow: on-line monitoring of growth and growth inhibition; segmentation of single cells and quantification of morphological features; and antimicrobial susceptibility testing. As oCelloScope enables the visualisation of low analyte concentrations, it also facilitates capturing the early stages in microbial growth that could not otherwise be detected with conventional OD measurements.